Representative Investments*


Zerigo Health, Inc.

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Zerigo Health offers the only comprehensive, clinically proven, at-home solution that seamlessly connects people with chronic skin conditions and providers to deliver optimal dermatological outcomes. Zerigo's precision solution is FDA-cleared for use on all skin types and remotely treats and monitors people with chronic skin conditions using narrowband ultraviolet B (NB-UVB) phototherapy, a proven, standard-of-care treatment. People benefit from the unique combination of advanced technology with personal coaching and support throughout their treatment journey, which results in documented increases in treatment adherence and patient satisfaction. The name Zerigo is derived from the primary disorders the company’s solution treats: eczema, psoriasis and vitiligo. These conditions affect over 30 million people in the U.S.

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Orasis Pharmaceuticals

Orasis Pharmaceuticals developed Qlosi™, an FDA approved corrective eye drop for the treatment of presbyopia in adults. Presbyopia is the gradual loss of an eye’s ability to focus on near objects, which begins to affect most people sometime after the age of 40 and affects more than 1.8 billion people worldwide. Orasis is led by a collaborative team of industry executives and eye care professionals with a broad range of experiences in research, development, and commercialization of pharmaceutical drugs, as well as finance and business development. Orasis is funded by a diverse group of sophisticated and experienced life science and healthcare investors.

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Continental Realty Group / CRA

This Denver, Colorado based company has been in the business of acquiring, renovating, owning, operating, and selling multi-family housing complexes nationwide for more than 25 years. Their proprietary system, AIM, allows them to manage the phases of the real estate investment process: Analysis-Investment-Management. Because of their track record and unique due diligence process, Bluestem has participated in a number of investments with this company and has invested in many properties in high growth markets.

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VIRUN, INC.

VIRUN, a Nutra-BioSciences® company, has developed over 200 fortified ingredients and finished beverage and supplement products; with over 60 patents and patent applications world-wide, focused on difficult-to-dissolve variants for food, beverage and supplement applications.  The ingredients are associated with health claims, such as: Cardiovascular Health, Energy and Cognitive Function, Weight Management, and Energy. VIRUN has successfully branded its OmegaH2O® Omega-3 EPA DHA, Coenzyme Clear® CoQ10, Esolv®, and DPtechnology® among other water soluble liquid and powder concentrates.

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EDCO

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EDCO Health Information Solutions designs, develops and implements software solutions for the health care industry in North America.  EDCO’s Solarity® software provides point of care batch scanning and indexing of patient medical records that complements electronic health record systems.  The end result is an accurate and complete electronic medical record, reduced costs, and improved patient outcomes. For more information visit http://www.solaritybyedco.com/

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Newton (formerly neurolens™, Inc.)

Newton is an innovation company redefining eye care through exceptional patient experiences and outcomes. Newton, named after Sir Isaac Newton, reflects the company’s commitment to challenging conventional standards in optometry and pioneering new frontiers that improve patient lives. Since 2012, Neurolenses, with the exclusive Contoured Prism™ technology, have brought relief to hundreds of thousands of patients struggling with the all-too-common symptoms of eye misalignment. The product is the only therapeutic lenses providing life-changing relief for headaches, motion sickness and neck pain. Sequel, their newest product line, represents Newton’s bold expansion into comprehensive vision care solutions. The portfolio expansion introduces an everyday lens that’s different from the rest. With patented Convergence Boost™ Technology, Sequel is effortless for providers to dispense and delivers impactful results for patients experiencing visual fatigue.

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Virtual Incision Corporation

Virtual Incision is on a mission to simplify robotic-assisted surgery (RAS), so more patients and their surgeons can access its benefits every day. Headquartered in Lincoln, Nebraska, and holding over two hundred patents and patent applications, the company is developing MIRA, the first-of-its-kind miniature RAS system. Virtual Incision’s goal is to make every operating room RAS-ready. 

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SYNQ3

This company, founded in 2007, specializes in operational and off-premise efficiencies for managing incoming calls for its restaurant industry customers. For the company’s fifteen national and regional customers, all phone-in-orders or catering calls from around the U.S. are handled at the Colorado Springs, CO headquarters. VIA, their Virtual Intelligent Assistant, enables measurement of guest experience, guest engagement, and order to-call ratios—metrics formerly unmeasurable in the restaurant industry.

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SpringCM

SpringCM is a secure document and contract management platform. Build workflows and enable document collaboration across your entire organization. Because when your documents flow, work flows.

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Surface Pharmaceuticals

A biopharmaceutical company focused on development and commercialization of innovative therapeutics for ocular diseases.

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POET

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POET, one of the world's largest ethanol producers, is a leader in biorefining through its efficient, vertically integrated approach to production. The 25-year-old company has a production capacity in excess of 1.6 billion gallons of ethanol and 9 billion pounds of high-protein animal feed annually from its network of 27 production facilities. POET also operates a pilot-scale cellulosic bio-ethanol plant, which uses corn cobs, leaves, husk and some stalk as feedstock, and expects to commercialize the process in Emmetsburg, Iowa through its joint venture with DSM.

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LENTECHS

LENTECHS, LLC is a privately held, clinical-stage ophthalmic medical device company, focused on developing a new generation of soft, suspended contact lenses. Headquartered in Columbus, Ohio, LENTECHS is backed by a network of investors who are truly committed to revolutionary innovation in contact lenses.

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Sydnexis, Inc.

Founded in 2014, Sydnexis is a privately held, pre-commercial biopharmaceutical company focused on decreasing the progression of myopia in children. Myopia currently affects 28 million children in the U.S. Sydnexis recently completed its three-year primary endpoint in a pivotal Phase 3 clinical trial evaluating its proprietary low-dose atropine formulation to slow progression of pediatric myopia and the risk of associated co-morbidities. The Phase 3 clinical trial is now completing the fourth-year randomized withdrawal for exploratory endpoints and third year results will be announced upon completion of the fourth year of the study. The company is venture-backed by four major investors: RA Capital, Longitude Capital, Visionary Ventures, and Bluestem Capital.

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Shoulder Innovations, Inc.

Shoulder Innovations Inc., based in Holland, Mich., is a medical device development company that designs and commercializes innovative products which demonstrate the potential for improved patient care and reduced overall cost to the healthcare system. Leveraging its breakthrough, patented, InSet™ glenoid design, Shoulder Innovations is commercializing a shoulder replacement implant system focused on improving outcomes related to the greatest cause of shoulder replacement failure: glenoid loosening. The InSet™ technology has been shown in multiple peer reviewed publications to significantly reduce glenoid implant micro-motion and simplifies the surgical technique, potentially reducing complications or increasing implant longevity.

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The Community Company

The Community Company builds and manages community-driven programs for media companies and global brands.

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